Silicone – established efficacy in scar management
Silicone gel sheeting is the choice of plastic surgeons worldwide [1]. A publication [1] by the International Advisory Panel on Scar Management, a group of skin specialists, recommended the use of Silicone Gel sheeting for the treatment of a wide variety of scars. Dermatologists and plastic surgeons have used Silicone Gel sheeting as an effective treatment for scars for many years. [2]
Unlike other scar treatments, Dermatix® products can be applied to all areas of the skin, including the face, joints and flexures. This gives you a choice of treatment options.
Several aspects of mechanisms [3-7]
For silicone, several mechanisms of action have been proposed in relation to scar management. However, the exact mechanism of action by which Silicone Gel works is still unknown.
Many have agreed that it acts at the stratum corneum (the uppermost layer of the epidermis), which reduces evaporation and restore homeostasis. A group of publications have also demonstrated the in-vitro, positive effect of silicone over growth factors and collagen concentration.
References
- Mustoe TA et al. Plast Reconstr Surg 2002;110:560-571
- Bayat A et al. BMJ 2003;326:88-92
- Quinn KJ. et al. Burns 1985;12:102–108
- Suetake T et al. Br J Plast Surg 2000;53:503-507
- Hirshowitz B et al. Plast Reconstr Surg 1998;101:1173-1183
- Chan KY et al. Plast Reconstr Surg 2005;116(4):1013-1020
